Isoform-Specific Effects of Apolipoprotein E on Markers of Inflammation and Toxicity in Brain Glia and Neuronal Cells In Vitro

Mutations to the cholesterol transport protein apolipoprotein E (ApoE) have been identified as a major risk factor for the development of sporadic or late-onset Alzheimer’s disease (AD), with the e4 allele representing an increased risk and the rare e2 allele having a reduced risk compared to the pr...

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Detalles Bibliográficos
Autores principales: Iannucci, Jaclyn, Sen, Abhik, Grammas, Paula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928993/
https://www.ncbi.nlm.nih.gov/pubmed/34071762
http://dx.doi.org/10.3390/cimb43010018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8928993/
https://www.ncbi.nlm.nih.gov/pubmed/34071762
http://dx.doi.org/10.3390/cimb43010018

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