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Molecular Genetics of Pre-B Acute Lymphoblastic Leukemia Sister Cell Lines during Disease Progression

For many years, immortalized tumor cell lines have been used as reliable tools to understand the function of oncogenes and tumor suppressor genes. Today, we know that tumors can comprise subclones with common and with subclone-specific genetic alterations. We sequenced DNA and RNA of sequential sist...

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Detalles Bibliográficos
Autores principales: Quentmeier, Hilmar, Pommerenke, Claudia, Drexler, Hans G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929001/
https://www.ncbi.nlm.nih.gov/pubmed/34940123
http://dx.doi.org/10.3390/cimb43030149