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In Silico Design of Dual-Binding Site Anti-Cholinesterase Phytochemical Heterodimers as Treatment Options for Alzheimer’s Disease

The number of patients with neurodegenerative diseases, particularly Alzheimer’s disease (AD), continues to grow yearly. Cholinesterase inhibitors (ChEIs) represent the first-line symptomatic drug treatment for mild-to-moderate AD; however, there is an unmet need to produce ChEIs with improved effic...

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Detalles Bibliográficos
Autores principales: Amat-ur-Rasool, Hafsa, Ahmed, Mehboob, Hasnain, Shahida, Ahmed, Abrar, Carter, Wayne Grant
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929005/
https://www.ncbi.nlm.nih.gov/pubmed/35723391
http://dx.doi.org/10.3390/cimb44010012