Biochemical, Biophysical and Functional Characterization of an Insoluble Iron Containing Hepcidin–Ferritin Chimeric Monomer Assembled Together with Human Ferritin H/L Chains at Different Molar Ratios

Hepcidin and ferritin are key proteins of iron homeostasis in mammals. In this study, we characterize a chimera by fusing camel hepcidin to a human ferritin H-chain to verify if it retained the properties of the two proteins. The construct (HepcH) is expressed in E. coli in an insoluble and iron-con...

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Detalles Bibliográficos
Autores principales: Boumaiza, Mohamed, Fhoula, Imene, Carmona, Fernando, Poli, Maura, Asperti, Michela, Gianoncelli, Alessandra, Bertuzzi, Michela, Arosio, Paolo, Marzouki, Mohamed Nejib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929011/
https://www.ncbi.nlm.nih.gov/pubmed/35723388
http://dx.doi.org/10.3390/cimb44010009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929011/
https://www.ncbi.nlm.nih.gov/pubmed/35723388
http://dx.doi.org/10.3390/cimb44010009

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