Oxidized Cell-Free DNA Rapidly Skews the Transcriptional Profile of Brain Cells toward Boosting Neurogenesis and Neuroplasticity

Cell-free DNA (cfDNA) is liberated and accumulated in neural tissue due to cell damage. The oxidative and nitrosative stress in the brain that accompanies various pathological conditions has been shown to increase the oxidation of cellular and cell-free DNA. Whether the high concentration of non-oxi...

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Detalles Bibliográficos
Autores principales: Filev, Anton D., Kostyuk, Svetlana V., Umriukhin, Pavel E., Pisarev, Vladimir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929019/
https://www.ncbi.nlm.nih.gov/pubmed/34698136
http://dx.doi.org/10.3390/cimb43030112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929019/
https://www.ncbi.nlm.nih.gov/pubmed/34698136
http://dx.doi.org/10.3390/cimb43030112

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