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Oxidized Cell-Free DNA Rapidly Skews the Transcriptional Profile of Brain Cells toward Boosting Neurogenesis and Neuroplasticity
Cell-free DNA (cfDNA) is liberated and accumulated in neural tissue due to cell damage. The oxidative and nitrosative stress in the brain that accompanies various pathological conditions has been shown to increase the oxidation of cellular and cell-free DNA. Whether the high concentration of non-oxi...
Autores principales: | Filev, Anton D., Kostyuk, Svetlana V., Umriukhin, Pavel E., Pisarev, Vladimir M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929019/ https://www.ncbi.nlm.nih.gov/pubmed/34698136 http://dx.doi.org/10.3390/cimb43030112 |
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