TET2 Mutation and High miR-22 Expression as Biomarkers to Predict Clinical Outcome in Myelodysplastic Syndrome Patients Treated with Hypomethylating Therapy

Tet methylcytosine dioxygenase 2 (TET2) is one of the most frequently mutated genes in myelodysplastic syndrome (MDS). TET2 is known to involve a demethylation process, and the loss of TET2 is thought to cause DNA hypermethylation. Loss of TET2 function is known to be caused by genetic mutations and...

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Detalles Bibliográficos
Autores principales: Yun, Jina, Ji, Young Sok, Jang, Geum Ha, Lim, Sung Hee, Kim, Se Hyung, Kim, Chan Kyu, Bae, Sang Byung, Won, Jong Ho, Park, Seong Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929064/
https://www.ncbi.nlm.nih.gov/pubmed/34449560
http://dx.doi.org/10.3390/cimb43020065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929064/
https://www.ncbi.nlm.nih.gov/pubmed/34449560
http://dx.doi.org/10.3390/cimb43020065

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