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Geraniol Averts Methotrexate-Induced Acute Kidney Injury via Keap1/Nrf2/HO-1 and MAPK/NF-κB Pathways

Objectives: Geraniol, a natural monoterpene, is an essential oil component of many plants. Methotrexate is an anti-metabolite drug, used for cancer and autoimmune conditions; however, clinical uses of methotrexate are limited by its concomitant renal injury. This study investigated the efficacy of g...

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Detalles Bibliográficos
Autores principales: Younis, Nancy S., Elsewedy, Heba S., Shehata, Tamer M., Mohamed, Maged E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929074/
https://www.ncbi.nlm.nih.gov/pubmed/34889889
http://dx.doi.org/10.3390/cimb43030123