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Poly(ADP-Ribose) Polymerase Inhibitor PJ34 Reduces Brain Damage after Stroke in the Neonatal Mouse Brain

The poly(ADP-ribose) polymerase inhibitor PJ34 has recently been reported to increase cerebral blood flow, via the endothelial NO synthase, in the naive mouse brain throughout life. We addressed here the benefits of PJ34 after neonatal ischemia on hemodynamics and components of the neurovascular uni...

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Detalles Bibliográficos
Autores principales: Bonnin, Philippe, Vitalis, Tania, Schwendimann, Leslie, Boutigny, Alexandre, Mohamedi, Nassim, Besson, Valérie C, Charriaut-Marlangue, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929080/
https://www.ncbi.nlm.nih.gov/pubmed/34200155
http://dx.doi.org/10.3390/cimb43010025