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Permeability of Gemcitabine and PBPK Modeling to Assess Oral Administration

Gemcitabine is a nucleoside analog effective against several solid tumors. Standard treatment consists of an intravenous infusion over 30 min. This is an invasive, uncomfortable and often painful method, involving recurring visits to the hospital and costs associated with medical staff and equipment...

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Detalles Bibliográficos
Autores principales: Ferreira, Abigail, Lapa, Rui, Vale, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929097/
https://www.ncbi.nlm.nih.gov/pubmed/34940127
http://dx.doi.org/10.3390/cimb43030153