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Permeability of Gemcitabine and PBPK Modeling to Assess Oral Administration
Gemcitabine is a nucleoside analog effective against several solid tumors. Standard treatment consists of an intravenous infusion over 30 min. This is an invasive, uncomfortable and often painful method, involving recurring visits to the hospital and costs associated with medical staff and equipment...
Autores principales: | Ferreira, Abigail, Lapa, Rui, Vale, Nuno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929097/ https://www.ncbi.nlm.nih.gov/pubmed/34940127 http://dx.doi.org/10.3390/cimb43030153 |
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