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Anti-Inflammatory Effect of Pineapple Rhizome Bromelain through Downregulation of the NF-κB- and MAPKs-Signaling Pathways in Lipopolysaccharide (LPS)-Stimulated RAW264.7 Cells

Bromelain is a mixture of proteolytic enzymes derived from pineapple (Ananas comosus) fruit and stem possessing several beneficial properties, particularly anti-inflammatory activity. However, the molecular mechanisms underlying the anti-inflammatory effects of bromelain are unclear. This study inve...

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Detalles Bibliográficos
Autores principales: Insuan, Orapin, Janchai, Phornphimon, Thongchuai, Benchaluk, Chaiwongsa, Rujirek, Khamchun, Supaporn, Saoin, Somphot, Insuan, Wimonrut, Pothacharoen, Peraphan, Apiwatanapiwat, Waraporn, Boondaeng, Antika, Vaithanomsat, Pilanee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929103/
https://www.ncbi.nlm.nih.gov/pubmed/34067064
http://dx.doi.org/10.3390/cimb43010008