Effect of Regorafenib on P2X7 Receptor Expression and Different Oncogenic Signaling Pathways in a Human Breast Cancer Cell Line: A Potential of New Insight of the Antitumor Effects of Regorafenib

Background: Breast cancer is the most common malignancy in women worldwide. P2X7 is a transmembrane receptor expressed in breast cancer and activated by the ATP tumor microenvironment, driving cell proliferation, angiogenesis, and metastasis via different signaling pathways. The role of the P2X7 rec...

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Detalles Bibliográficos
Autores principales: Salahuddin, Muhammed M., Omran, Gamal A., Helmy, Maged W., Houssen, Maha E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929109/
https://www.ncbi.nlm.nih.gov/pubmed/34940128
http://dx.doi.org/10.3390/cimb43030154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929109/
https://www.ncbi.nlm.nih.gov/pubmed/34940128
http://dx.doi.org/10.3390/cimb43030154

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