KPNB1 Inhibitor Importazole Reduces Ionizing Radiation-Increased Cell Surface PD-L1 Expression by Modulating Expression and Nuclear Import of IRF1

Programmed death-ligand 1 (PD-L1) is an immune checkpoint molecule that negatively regulates anti-tumor immunity. Recent reports indicate that anti-cancer treatments, such as radiation therapy, increase PD-L1 expression on the surface of tumor cells. We previously reported that the nuclear transport...

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Detalles Bibliográficos
Autores principales: Yoshino, Hironori, Sato, Yoshiaki, Nakano, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929148/
https://www.ncbi.nlm.nih.gov/pubmed/34069326
http://dx.doi.org/10.3390/cimb43010013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929148/
https://www.ncbi.nlm.nih.gov/pubmed/34069326
http://dx.doi.org/10.3390/cimb43010013

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