Metabolism and disposition of opicapone in the rat and metabolic enzymes phenotyping

Opicapone (2,5‐dichloro‐3‐(5‐(3,4‐dihydroxy‐5‐nitrophenyl)‐1,2,4‐oxadiazol‐3‐yl)‐4,6‐dimethylpyridine 1‐oxide) is a selective catechol‐O‐methyltransferase inhibitor that has been granted marketing authorization in Europe, Japan, and United States. The present work describes the metabolism and dispos...

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Detalles Bibliográficos
Autores principales: Loureiro, Ana I., Fernandes‐Lopes, Carlos, Bonifácio, Maria João, Sousa, Filipa, Kiss, László E., Soares‐da‐Silva, Patricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929358/
https://www.ncbi.nlm.nih.gov/pubmed/34939338
http://dx.doi.org/10.1002/prp2.891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929358/
https://www.ncbi.nlm.nih.gov/pubmed/34939338
http://dx.doi.org/10.1002/prp2.891

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