The Pseudomonas aeruginosa Type III Secretion System Exoenzyme Effector ExoU Induces Mitochondrial Damage in a Murine Bone Marrow-Derived Macrophage Infection Model

Pseudomonas aeruginosa is a Gram-negative, opportunistic pathogen that causes nosocomial pneumonia, urinary tract infections, and bacteremia. A hallmark of P. aeruginosa pathogenesis is disruption of host cell function by the type III secretion system (T3SS) and its cognate exoenzyme effectors. The...

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Detalles Bibliográficos
Autores principales: Hardy, Kierra S., Tuckey, Amanda N., Housley, Nicole A., Andrews, Joel, Patel, Mita, Al-Mehdi, Abu-Bakr, Barrington, Robert A., Cassel, Suzanne L., Sutterwala, Fayyaz S., Audia, Jonathon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929383/
https://www.ncbi.nlm.nih.gov/pubmed/35130452
http://dx.doi.org/10.1128/iai.00470-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929383/
https://www.ncbi.nlm.nih.gov/pubmed/35130452
http://dx.doi.org/10.1128/iai.00470-21

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