Human Retinal Organoids Provide a Suitable Tool for Toxicological Investigations: A Comprehensive Validation Using Drugs and Compounds Affecting the Retina

Retinal drug toxicity screening is essential for the development of safe treatment strategies for a large number of diseases. To this end, retinal organoids derived from human pluripotent stem cells (hPSCs) provide a suitable screening platform due to their similarity to the human retina and the eas...

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Detalles Bibliográficos
Autores principales: Dorgau, Birthe, Georgiou, Maria, Chaudhary, Alexander, Moya-Molina, Marina, Collin, Joseph, Queen, Rachel, Hilgen, Gerrit, Davey, Tracey, Hewitt, Philip, Schmitt, Michael, Kustermann, Stefan, Pognan, Francois, Steel, David H, Sernagor, Evelyne, Armstrong, Lyle, Lako, Majlinda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Cell Based Drug Development, Screening, and Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929478/
https://www.ncbi.nlm.nih.gov/pubmed/35298655
http://dx.doi.org/10.1093/stcltm/szab010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929478/
https://www.ncbi.nlm.nih.gov/pubmed/35298655
http://dx.doi.org/10.1093/stcltm/szab010

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