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Intranasal delivery of SARS-CoV-2 spike protein is sufficient to cause olfactory damage, inflammation and olfactory dysfunction in zebrafish

Anosmia, loss of smell, is a prevalent symptom of SARS-CoV-2 infection. Anosmia may be explained by several mechanisms driven by infection of non-neuronal cells and damage in the nasal epithelium rather than direct infection of olfactory sensory neurons (OSNs). Previously, we showed that viral prote...

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Detalles Bibliográficos
Autores principales: Kraus, Aurora, Huertas, Mar, Ellis, Laura, Boudinot, Pierre, Levraud, Jean-Pierre, Salinas, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929544/
https://www.ncbi.nlm.nih.gov/pubmed/35307504
http://dx.doi.org/10.1016/j.bbi.2022.03.006