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A TCR mimic monoclonal antibody for the HPV-16 E7-epitope p11-19/HLA-A*02:01 complex

More effective treatments are needed for human papilloma virus (HPV)-induced cancers despite HPV virus vaccination. The oncogenic HPV protein targets are currently undruggable and intracellular and therefore there are no antibodies to these targets. Here we report the discovery of TCR mimic monoclon...

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Detalles Bibliográficos
Autores principales: Dao, Tao, Mun, Sungsoo, Korontsvit, Tatyana, Khan, Abdul G., Pohl, Mary Ann, White, Thomas, Klatt, Martin G., Andrew, David, Lorenz, Ivo C., Scheinberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929633/
https://www.ncbi.nlm.nih.gov/pubmed/35298559
http://dx.doi.org/10.1371/journal.pone.0265534