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A TCR mimic monoclonal antibody for the HPV-16 E7-epitope p11-19/HLA-A*02:01 complex
More effective treatments are needed for human papilloma virus (HPV)-induced cancers despite HPV virus vaccination. The oncogenic HPV protein targets are currently undruggable and intracellular and therefore there are no antibodies to these targets. Here we report the discovery of TCR mimic monoclon...
Autores principales: | Dao, Tao, Mun, Sungsoo, Korontsvit, Tatyana, Khan, Abdul G., Pohl, Mary Ann, White, Thomas, Klatt, Martin G., Andrew, David, Lorenz, Ivo C., Scheinberg, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929633/ https://www.ncbi.nlm.nih.gov/pubmed/35298559 http://dx.doi.org/10.1371/journal.pone.0265534 |
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