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Model-based identification of conditionally-essential genes from transposon-insertion sequencing data

The understanding of bacterial gene function has been greatly enhanced by recent advancements in the deep sequencing of microbial genomes. Transposon insertion sequencing methods combines next-generation sequencing techniques with transposon mutagenesis for the exploration of the essentiality of gen...

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Detalles Bibliográficos
Autores principales: Sarsani, Vishal, Aldikacti, Berent, He, Shai, Zeinert, Rilee, Chien, Peter, Flaherty, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929702/
https://www.ncbi.nlm.nih.gov/pubmed/35255084
http://dx.doi.org/10.1371/journal.pcbi.1009273