Effects of Lamotrigine and Topiramate on Glial Properties in an Astrocyte-Microglia Co-Culture Model of Inflammation

BACKGROUND: Astrocytes and microglia are involved in the pathophysiology of epilepsy and bipolar disorder with a link to inflammation. We aimed to investigate the effects of the antiepileptic and mood-stabilizing drugs lamotrigine (LTG) and topiramate (TPM) on glial viability, microglial activation,...

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Detalles Bibliográficos
Autores principales: Faustmann, Timo Jendrik, Corvace, Franco, Faustmann, Pedro M, Ismail, Fatme Seval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Regular Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929754/
https://www.ncbi.nlm.nih.gov/pubmed/34791253
http://dx.doi.org/10.1093/ijnp/pyab080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8929754/
https://www.ncbi.nlm.nih.gov/pubmed/34791253
http://dx.doi.org/10.1093/ijnp/pyab080

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