SERCA2a stimulation by istaroxime improves intracellular Ca(2+) handling and diastolic dysfunction in a model of diabetic cardiomyopathy

AIMS : Diabetic cardiomyopathy is a multifactorial disease characterized by an early onset of diastolic dysfunction (DD) that precedes the development of systolic impairment. Mechanisms that can restore cardiac relaxation improving intracellular Ca(2+) dynamics represent a promising therapeutic appr...

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Detalles Bibliográficos
Autores principales: Torre, Eleonora, Arici, Martina, Lodrini, Alessandra Maria, Ferrandi, Mara, Barassi, Paolo, Hsu, Shih-Che, Chang, Gwo-Jyh, Boz, Elisabetta, Sala, Emanuela, Vagni, Sara, Altomare, Claudia, Mostacciuolo, Gaspare, Bussadori, Claudio, Ferrari, Patrizia, Bianchi, Giuseppe, Rocchetti, Marcella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930067/
https://www.ncbi.nlm.nih.gov/pubmed/33792692
http://dx.doi.org/10.1093/cvr/cvab123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930067/
https://www.ncbi.nlm.nih.gov/pubmed/33792692
http://dx.doi.org/10.1093/cvr/cvab123

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