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Reduced DMPC and PMPC in lung surfactant promote SARS-CoV-2 infection in obesity

OBJECTIVE: Obesity is an established risk factor for higher SARS-CoV-2 viral loads, severe COVID-19 pneumonia requiring hospitalization, and worse outcomes. However, the underlying mechanisms for the increased risk are not well understood. SARS-CoV-2 is a respiratory virus with the primary route of...

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Detalles Bibliográficos
Autores principales: Du, Kang, Sun, Ling, Luo, Zichen, Cao, Yang, Sun, Qiushi, Zhang, Kangzhen, Faizy, Ahmed, Piomelli, Daniele, Lu, Xiang, Shan, Jinjun, Yang, Qin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930181/
https://www.ncbi.nlm.nih.gov/pubmed/35311662
http://dx.doi.org/10.1016/j.metabol.2022.155181