Cargando…

Licochalcone A Promotes the Ubiquitination of c-Met to Abrogate Gefitinib Resistance

Met proto-oncogene (MET) amplification and tyrosine-protein kinase Met (c-Met) overexpression confer gefitinib resistance in non-small cell lung cancer (NSCLC). The natural product Licochalcone A (Lico A) exhibits a broad range of inhibitory effects against various tumors. However, the effects of Li...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Shuangze, Li, Xiaoying, Gan, Yu, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930240/
https://www.ncbi.nlm.nih.gov/pubmed/35309168
http://dx.doi.org/10.1155/2022/5687832