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Licochalcone A Promotes the Ubiquitination of c-Met to Abrogate Gefitinib Resistance
Met proto-oncogene (MET) amplification and tyrosine-protein kinase Met (c-Met) overexpression confer gefitinib resistance in non-small cell lung cancer (NSCLC). The natural product Licochalcone A (Lico A) exhibits a broad range of inhibitory effects against various tumors. However, the effects of Li...
Autores principales: | Han, Shuangze, Li, Xiaoying, Gan, Yu, Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930240/ https://www.ncbi.nlm.nih.gov/pubmed/35309168 http://dx.doi.org/10.1155/2022/5687832 |
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