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Polymorphic mutations in the polb gene promoter and their impact on transcriptional activity

BACKGROUND: DNA polymerase β is one of the key enzymes involved in DNA damage repair and its proper expression is strictly controlled within different cells. We previously reported that three genetic mutations in the promoter region of the polb gene are prevalent in the Chinese Han population and tw...

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Detalles Bibliográficos
Autores principales: Wu, Qingjun, Qi, Yuying, Wang, Shuanghu, Liu, Jian, Geng, Peiwu, Zhou, Quan, Zhang, Wenqian, Cai, Jianping, Hu, Bin, Dai, Dapeng, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930491/
https://www.ncbi.nlm.nih.gov/pubmed/35128818
http://dx.doi.org/10.1111/1759-7714.14337