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Polymorphic mutations in the polb gene promoter and their impact on transcriptional activity
BACKGROUND: DNA polymerase β is one of the key enzymes involved in DNA damage repair and its proper expression is strictly controlled within different cells. We previously reported that three genetic mutations in the promoter region of the polb gene are prevalent in the Chinese Han population and tw...
Autores principales: | Wu, Qingjun, Qi, Yuying, Wang, Shuanghu, Liu, Jian, Geng, Peiwu, Zhou, Quan, Zhang, Wenqian, Cai, Jianping, Hu, Bin, Dai, Dapeng, Li, Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930491/ https://www.ncbi.nlm.nih.gov/pubmed/35128818 http://dx.doi.org/10.1111/1759-7714.14337 |
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