YAP/TAZ drives cell proliferation and tumor growth via a polyamine-eIF5A hypusination-LSD1 axis

Metabolic reprogramming is central to oncogene-induced tumorigenesis by providing the necessary building blocks and energy sources, but how oncogenic signaling controls metabolites that play regulatory roles in driving cell proliferation and tumor growth is less understood. Here we show that oncogen...

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Detalles Bibliográficos
Autores principales: Li, Hongde, Wu, Bo-Kuan, Kanchwala, Mohammed, Cai, Jing, Wang, Li, Xing, Chao, Zheng, Yonggang, Pan, Duojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930503/
https://www.ncbi.nlm.nih.gov/pubmed/35177822
http://dx.doi.org/10.1038/s41556-022-00848-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930503/
https://www.ncbi.nlm.nih.gov/pubmed/35177822
http://dx.doi.org/10.1038/s41556-022-00848-5

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