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YAP/TAZ drives cell proliferation and tumor growth via a polyamine-eIF5A hypusination-LSD1 axis
Metabolic reprogramming is central to oncogene-induced tumorigenesis by providing the necessary building blocks and energy sources, but how oncogenic signaling controls metabolites that play regulatory roles in driving cell proliferation and tumor growth is less understood. Here we show that oncogen...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930503/ https://www.ncbi.nlm.nih.gov/pubmed/35177822 http://dx.doi.org/10.1038/s41556-022-00848-5 |