Seipin forms a flexible cage at lipid droplet formation sites

Lipid droplets (LDs) form in the endoplasmic reticulum by phase separation of neutral lipids. This process is facilitated by the seipin protein complex, which consists of a ring of seipin monomers, with a yet unclear function. Here, we report a structure of S. cerevisiae seipin based on cryogenic-el...

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Detalles Bibliográficos
Autores principales: Arlt, Henning, Sui, Xuewu, Folger, Brayden, Adams, Carson, Chen, Xiao, Remme, Roman, Hamprecht, Fred A., DiMaio, Frank, Liao, Maofu, Goodman, Joel M., Farese, Robert V., Walther, Tobias C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930772/
https://www.ncbi.nlm.nih.gov/pubmed/35210614
http://dx.doi.org/10.1038/s41594-021-00718-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930772/
https://www.ncbi.nlm.nih.gov/pubmed/35210614
http://dx.doi.org/10.1038/s41594-021-00718-y

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