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CEBPβ regulation of endogenous IGF-1 in adult sensory neurons can be mobilized to overcome diabetes-induced deficits in bioenergetics and axonal outgrowth
Aberrant insulin-like growth factor 1 (IGF-1) signaling has been proposed as a contributing factor to the development of neurodegenerative disorders including diabetic neuropathy, and delivery of exogenous IGF-1 has been explored as a treatment for Alzheimer’s disease and amyotrophic lateral scleros...
Autores principales: | Aghanoori, Mohamad-Reza, Agarwal, Prasoon, Gauvin, Evan, Nagalingam, Raghu S., Bonomo, Raiza, Yathindranath, Vinith, Smith, Darrell R., Hai, Yan, Lee, Samantha, Jolivalt, Corinne G., Calcutt, Nigel A., Jones, Meaghan J., Czubryt, Michael P., Miller, Donald W., Dolinsky, Vernon W., Mansuy-Aubert, Virginie, Fernyhough, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930798/ https://www.ncbi.nlm.nih.gov/pubmed/35298717 http://dx.doi.org/10.1007/s00018-022-04201-9 |
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