Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors

PURPOSE: Low-grade gliomas (LGG) and mixed neuronal-glial tumors (MNGT) show frequent MAPK pathway alterations. Oncogenic fibroblast growth factor receptor 1 (FGFR1) tyrosinase kinase domain has been reported in brain tumors of various histologies. We sought to determine the frequency of FGFR1 hotsp...

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Detalles Bibliográficos
Autores principales: Engelhardt, Sophie, Behling, Felix, Beschorner, Rudi, Eckert, Franziska, Kohlhof, Patricia, Tatagiba, Marcos, Tabatabai, Ghazaleh, Schuhmann, Martin U., Ebinger, Martin, Schittenhelm, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Article – Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930952/
https://www.ncbi.nlm.nih.gov/pubmed/35018490
http://dx.doi.org/10.1007/s00432-021-03906-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930952/
https://www.ncbi.nlm.nih.gov/pubmed/35018490
http://dx.doi.org/10.1007/s00432-021-03906-x

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