Cargando…

Frequent FGFR1 hotspot alterations in driver-unknown low-grade glioma and mixed neuronal-glial tumors

PURPOSE: Low-grade gliomas (LGG) and mixed neuronal-glial tumors (MNGT) show frequent MAPK pathway alterations. Oncogenic fibroblast growth factor receptor 1 (FGFR1) tyrosinase kinase domain has been reported in brain tumors of various histologies. We sought to determine the frequency of FGFR1 hotsp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Engelhardt, Sophie, Behling, Felix, Beschorner, Rudi, Eckert, Franziska, Kohlhof, Patricia, Tatagiba, Marcos, Tabatabai, Ghazaleh, Schuhmann, Martin U., Ebinger, Martin, Schittenhelm, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Original Article – Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930952/ https://www.ncbi.nlm.nih.gov/pubmed/35018490 http://dx.doi.org/10.1007/s00432-021-03906-x

Ejemplares similares

COX2 expression is associated with proliferation and tumor extension in vestibular schwannoma but is not influenced by acetylsalicylic acid intake
por: Behling, Felix, et al.
Publicado: (2019)

High Expression of Somatostatin Receptors 2A, 3, and 5 in Corticotroph Pituitary Adenoma
por: Behling, Felix, et al.
Publicado: (2018)

COX2 expression is associated with preoperative tumor volume but not with volumetric tumor growth in vestibular schwannoma
por: Behling, Felix, et al.
Publicado: (2021)

PAX6 is frequently expressed in ependymal tumours and associated with prognostic relevant subgroups
por: Tabasaran, Julian, et al.
Publicado: (2022)

The prognostic role of the immunohistochemical expression of S100 in meningiomas
por: Behling, Felix, et al.
Publicado: (2022)

Macrophage and Lymphocyte Infiltration Is Associated with Volumetric Tumor Size but Not with Volumetric Growth in the Tübingen Schwannoma Cohort
por: Gonçalves, Vítor Moura, et al.
Publicado: (2021)

The role of Simpson grading in meningiomas after integration of the updated WHO classification and adjuvant radiotherapy
por: Behling, Felix, et al.
Publicado: (2020)

Differences in the expression of SSTR1–5 in meningiomas and its therapeutic potential
por: Behling, Felix, et al.
Publicado: (2021)

Correction: Gonçalves et al. Macrophage and Lymphocyte Infiltration Is Associated with Volumetric Tumor Size but Not with Volumetric Growth in the Tübingen Schwannoma Cohort. Cancers 2021, 13, 466
por: Gonçalves, Vítor Moura, et al.
Publicado: (2023)

Increased proliferation is associated with CNS invasion in meningiomas
por: Behling, Felix, et al.
Publicado: (2021)

Correction to: The immunohistochemical expression of SSTR2A is an independent prognostic factor in meningioma
por: Fodi, Christina, et al.
Publicado: (2022)

The immunohistochemical expression of SSTR2A is an independent prognostic factor in meningioma
por: Fodi, Christina, et al.
Publicado: (2021)

Integrative assessment of brain and bone invasion in meningioma patients
por: Zwirner, Kerstin, et al.
Publicado: (2019)

Surgical Management of Pre-Chiasmatic Intraorbital Optic Nerve Gliomas in Children after Loss of Visual Function—Resection from Bulbus to Chiasm
por: Zipfel, Julian, et al.
Publicado: (2022)

CNS Invasion in Meningioma—How the Intraoperative Assessment Can Improve the Prognostic Evaluation of Tumor Recurrence
por: Behling, Felix, et al.
Publicado: (2020)

H3K27me3 loss indicates an increased risk of recurrence in the Tübingen meningioma cohort
por: Behling, Felix, et al.
Publicado: (2020)

Retrospective analysis of recurrence patterns and clinical outcome of grade II meningiomas following postoperative radiotherapy
por: Hoffmann, Elgin, et al.
Publicado: (2021)

ATRX immunostaining predicts IDH and H3F3A status in gliomas
por: Ebrahimi, Azadeh, et al.
Publicado: (2016)

ADC-Based Stratification of Molecular Glioma Subtypes Using High b-Value Diffusion-Weighted Imaging
por: Nuessle, Nils C., et al.
Publicado: (2021)

A Continuous Correlation Between Residual Tumor Volume and Survival Recommends Maximal Safe Resection in Glioblastoma Patients: A Nomogram for Clinical Decision Making and Reference for Non-Randomized Trials
por: Skardelly, Marco, et al.
Publicado: (2021)

Glioma-Specific Diffusion Signature in Diffusion Kurtosis Imaging
por: Hempel, Johann-Martin, et al.
Publicado: (2021)

Transition of a vestibular schwannoma to a malignant peripheral nerve sheath tumor with loss of H3K27 trimethylation after radiosurgery—a case report and review of the literature
por: Behling, Felix, et al.
Publicado: (2021)

Loss of H3K27me3 in meningiomas: an independent marker for CNS WHO grade 2?
por: Behling, Felix, et al.
Publicado: (2023)

Brain Invasion in Meningioma—A Prognostic Potential Worth Exploring
por: Behling, Felix, et al.
Publicado: (2021)

Mass Extinction and the Disappearance of Unknown Mammal Species: Scenario and Perspectives of a Biodiversity Hotspot’s Hotspot
por: Mendes Pontes, Antonio Rossano, et al.
Publicado: (2016)

LGG-51. Resection extent and BRAF V600E mutation status determine postoperative growth velocity in pediatric Low-grade glioma: Results from a single-center cohort analysis
por: Gorodezki, David, et al.
Publicado: (2022)

Correction to: Association of dynamic susceptibility magnetic resonance imaging at initial tumor diagnosis with the prognosis of different molecular glioma subtypes
por: Brendle, Cornelia, et al.
Publicado: (2021)

Association of dynamic susceptibility magnetic resonance imaging at initial tumor diagnosis with the prognosis of different molecular glioma subtypes
por: Brendle, Cornelia, et al.
Publicado: (2020)

Oncogenic BRAF Alterations and Their Role in Brain Tumors
por: Behling, Felix, et al.
Publicado: (2019)

FGFR3IIIS: a novel soluble FGFR3 spliced variant that modulates growth is frequently expressed in tumour cells
por: Sturla, L-M, et al.
Publicado: (2003)

Resection extent and BRAF V600E mutation status determine postoperative tumor growth velocity in pediatric low-grade glioma: results from a single-center cohort analysis
por: Gorodezki, David, et al.
Publicado: (2022)

FGFR4 overexpression and hotspot mutations in metastatic ER+ breast cancer are enriched in the lobular subtype
por: Levine, Kevin M., et al.
Publicado: (2019)

Frequent 4EBP1 Amplification Induces Synthetic Dependence on FGFR Signaling in Cancer
por: Mohan, Prathibha, et al.
Publicado: (2022)

KIAA1549: BRAF Gene Fusion and FGFR1 Hotspot Mutations Are Prognostic Factors in Pilocytic Astrocytomas
por: Becker, Aline Paixão, et al.
Publicado: (2015)

Dynamic Susceptibility Perfusion Imaging for Differentiating Progressive Disease from Pseudoprogression in Diffuse Glioma Molecular Subtypes
por: Richter, Vivien, et al.
Publicado: (2021)

Frequency of BRAF V600E mutations in 969 central nervous system neoplasms
por: Behling, Felix, et al.
Publicado: (2016)

Aguascalientes: one of the hottest chronic kidney disease (CKD) hotspots in Mexico and a CKD of unknown aetiology mystery to be solved
por: Villalvazo, Priscila, et al.
Publicado: (2021)

Searching for longevity hotspots in Denmark
por: Hansen, Anne Vinkel, et al.
Publicado: (2018)

A polymorphic AT-repeat causes frequent allele dropout for an MME mutational hotspot exon
por: Høyer, Helle, et al.
Publicado: (2022)

Contribution of mTOR and PTEN to Radioresistance in Sporadic and NF2-Associated Vestibular Schwannomas: A Microarray and Pathway Analysis
por: Gugel, Isabel, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0hvfsr7so3j2779arap0fb6u5i