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Orexin A peptidergic system: comparative sleep behavior, morphology and population in brains between wild type and Alzheimer’s disease mice

Sleep disturbance is common in patients with Alzheimer’s disease (AD), and orexin A is a pivotal neurotransmitter for bidirectionally regulating the amyloid-β (Aβ) deposition of AD brain and poor sleep. In the present study, we examined the characteristic of sleep–wake architecture in APPswe/PSldE9...

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Detalles Bibliográficos
Autores principales: Zhao, Peng, You, Yaqian, Wang, Zhe, Zhou, Yanjun, Chai, Gaoshang, Yan, Gen, Jin, Zhewu, Wang, Qing, Sun, Hongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930968/
https://www.ncbi.nlm.nih.gov/pubmed/35066609
http://dx.doi.org/10.1007/s00429-021-02447-w