Homeostatic serum IgE is secreted by plasma cells in the thymus and enhances mast cell survival

Increased serum levels of immunoglobulin E (IgE) is a risk factor for various diseases, including allergy and anaphylaxis. However, the source and ontogeny of B cells producing IgE under steady state conditions are not well defined. Here, we show plasma cells that develop in the thymus and potently...

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Detalles Bibliográficos
Autores principales: Kwon, Dong-il, Park, Eun Seo, Kim, Mingyu, Choi, Yoon Ha, Lee, Myeong-seok, Joo, Si-hyung, Kang, Yeon-Woo, Lee, Minji, Jo, Saet-byeol, Lee, Seung-Woo, Kim, Jong Kyoung, Lee, You Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930980/
https://www.ncbi.nlm.nih.gov/pubmed/35301301
http://dx.doi.org/10.1038/s41467-022-29032-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930980/
https://www.ncbi.nlm.nih.gov/pubmed/35301301
http://dx.doi.org/10.1038/s41467-022-29032-x

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