Structural basis for activation and gating of IP(3) receptors

A pivotal component of the calcium (Ca(2+)) signaling toolbox in cells is the inositol 1,4,5-triphosphate (IP(3)) receptor (IP(3)R), which mediates Ca(2+) release from the endoplasmic reticulum (ER), controlling cytoplasmic and organellar Ca(2+) concentrations. IP(3)Rs are co-activated by IP(3) and...

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Detalles Bibliográficos
Autores principales: Schmitz, Emily A., Takahashi, Hirohide, Karakas, Erkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930994/
https://www.ncbi.nlm.nih.gov/pubmed/35301323
http://dx.doi.org/10.1038/s41467-022-29073-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930994/
https://www.ncbi.nlm.nih.gov/pubmed/35301323
http://dx.doi.org/10.1038/s41467-022-29073-2

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