Cargando…

Structural basis for activation and gating of IP(3) receptors

A pivotal component of the calcium (Ca(2+)) signaling toolbox in cells is the inositol 1,4,5-triphosphate (IP(3)) receptor (IP(3)R), which mediates Ca(2+) release from the endoplasmic reticulum (ER), controlling cytoplasmic and organellar Ca(2+) concentrations. IP(3)Rs are co-activated by IP(3) and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schmitz, Emily A., Takahashi, Hirohide, Karakas, Erkan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930994/ https://www.ncbi.nlm.nih.gov/pubmed/35301323 http://dx.doi.org/10.1038/s41467-022-29073-2

Ejemplares similares

Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly
por: Takahashi, Hirohide, et al.
Publicado: (2023)

Structural basis for the regulation of inositol trisphosphate receptors by Ca(2+) and IP(3)
por: Paknejad, Navid, et al.
Publicado: (2018)

Structural basis for the coiled-coil architecture of human CtIP
por: Morton, C. R., et al.
Publicado: (2021)

Structural Basis for Gating Pore Current in Periodic Paralysis
por: Jiang, Daohua, et al.
Publicado: (2018)

Clustering of IP(3) receptors by IP(3) retunes their regulation by IP(3) and Ca(2+)
por: Taufiq-Ur-Rahman,, et al.
Publicado: (2009)

On The Structural Basis of Modal Gating Behavior in K(+) Channels
por: Chakrapani, Sudha, et al.
Publicado: (2010)

Structural basis for gating mechanism of Pannexin 1 channel
por: Mou, Luqiu, et al.
Publicado: (2020)

Structural basis of the activation of metabotropic glutamate receptor 3
por: Fang, Wei, et al.
Publicado: (2022)

Structural basis for gating mechanism of the human sodium-potassium pump
por: Nguyen, Phong T., et al.
Publicado: (2022)

Structural basis of gating modulation of Kv4 channel complexes
por: Kise, Yoshiaki, et al.
Publicado: (2021)

Analyzing and Quantifying the Gain-of-Function Enhancement of IP(3) Receptor Gating by Familial Alzheimer’s Disease-Causing Mutants in Presenilins
por: Mak, Don-On Daniel, et al.
Publicado: (2015)

Synthetic partial agonists reveal key steps in IP(3) receptor activation
por: Rossi, Ana M., et al.
Publicado: (2009)

Activation of IP(3) receptors by synthetic bisphosphate ligands
por: Sureshan, Kana M., et al.
Publicado: (2009)

Progress in the Structural Basis of thermoTRP Channel Polymodal Gating
por: Fernández-Ballester, Gregorio, et al.
Publicado: (2023)

Conformational motions and ligand-binding underlying gating and regulation in IP(3)R channel
por: Fan, Guizhen, et al.
Publicado: (2022)

Selective coupling of type 6 adenylyl cyclase with type 2 IP(3) receptors mediates direct sensitization of IP(3) receptors by cAMP
por: Tovey, Stephen C., et al.
Publicado: (2008)

Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
por: Laponogov, Ivan, et al.
Publicado: (2010)

A physical basis for quantitative ChIP-sequencing
por: Dickson, Bradley M., et al.
Publicado: (2020)

Structural basis for selective activation of ABA receptors
por: Peterson, Francis C., et al.
Publicado: (2010)

Structural basis of calmodulin modulation of the rod cyclic nucleotide-gated channel
por: Barret, Diane C. A., et al.
Publicado: (2023)

Triplin: Mechanistic Basis for Voltage Gating
por: Colombini, Marco, et al.
Publicado: (2023)

Structural basis of the activation of c-MET receptor
por: Uchikawa, Emiko, et al.
Publicado: (2021)

Structural basis for Ca(2+) selectivity of a voltage-gated calcium channel
por: Tang, Lin, et al.
Publicado: (2013)

OR30-3 Structural Basis of Activation and Sustained Signaling by the PTH Receptor
por: Sutkeviciute, Ieva, et al.
Publicado: (2019)

Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
por: Sauguet, Ludovic, et al.
Publicado: (2013)

Structural basis for the inhibition of voltage-dependent K(+) channel by gating modifier toxin
por: Ozawa, Shin-ichiro, et al.
Publicado: (2015)

Activation of NMDA receptors and the mechanism of inhibition by ifenprodil
por: Tajima, Nami, et al.
Publicado: (2016)

Structural basis of ion permeation gating in Slo2.1 K(+) channels
por: Garg, Priyanka, et al.
Publicado: (2013)

Correction: Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
por: Laponogov, Ivan, et al.
Publicado: (2010)

Correction: Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases
por: Laponogov, Ivan, et al.
Publicado: (2010)

Type 3 IP3 receptor: Its structure, functions, and related disease implications
por: Wu, Lvying, et al.
Publicado: (2023)

Stimulation of Inositol 1,4,5-Trisphosphate (IP(3)) Receptor Subtypes by Analogues of IP(3)
por: Saleem, Huma, et al.
Publicado: (2013)

Subunit Arrangement and Phenylethanolamine Binding in GluN1/GluN2B NMDA Receptors
por: Karakas, Erkan, et al.
Publicado: (2011)

Structural basis of the activation of a metabotropic GABA receptor
por: Shaye, Hamidreza, et al.
Publicado: (2020)

Structural basis of peptide recognition and activation of endothelin receptors
por: Ji, Yujie, et al.
Publicado: (2023)

Structural basis of transcobalamin recognition by human CD320 receptor
por: Alam, Amer, et al.
Publicado: (2016)

Structural basis of the effect of activating mutations on the EGF receptor
por: Galdadas, Ioannis, et al.
Publicado: (2021)

Structural titration reveals Ca(2+)-dependent conformational landscape of the IP(3) receptor
por: Paknejad, Navid, et al.
Publicado: (2023)

Regulation of IP(3) receptors by cyclic AMP
por: Taylor, Colin W.
Publicado: (2017)

Chemokine receptor specific for IP10 and mig: structure, function, and expression in activated T-lymphocytes
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_aoqv34sdl70nbeds88tmv2cvv3