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Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor

Progressive degeneration of dopaminergic (DA) neurons in the substantia nigra is a hallmark of Parkinson’s disease (PD). Dysregulation of developmental transcription factors is implicated in dopaminergic neurodegeneration, but the underlying molecular mechanisms remain largely unknown. Drosophila Fe...

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Detalles Bibliográficos
Autores principales: Miozzo, Federico, Valencia-Alarcón, Eva P., Stickley, Luca, Majcin Dorcikova, Michaëla, Petrelli, Francesco, Tas, Damla, Loncle, Nicolas, Nikonenko, Irina, Bou Dib, Peter, Nagoshi, Emi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931002/
https://www.ncbi.nlm.nih.gov/pubmed/35301315
http://dx.doi.org/10.1038/s41467-022-29075-0