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Canonical and Non-Canonical Functions of the Autophagy Machinery in MHC Restricted Antigen Presentation
Macroautophagy delivers cytoplasmic constituents for lysosomal degradation. Since major histocompatibility complex (MHC) class II molecules sample peptides after lysosomal degradation for presentation to CD4(+) T cells, it was originally described that these peptides can also originate from macroaut...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931038/ https://www.ncbi.nlm.nih.gov/pubmed/35309359 http://dx.doi.org/10.3389/fimmu.2022.868888 |