Morphine-induced modulation of Nrf2-antioxidant response element signaling pathway in primary human brain microvascular endothelial cells

Morphine is one of the most potent opioid analgesic used for pain treatment. Morphine action in the central nervous system requires crossing the blood–brain barrier. Due to the controversial relationship between morphine and oxidative stress, the potential pro- or antioxidant effects of morphine in...

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Detalles Bibliográficos
Autores principales: Reymond, Sandrine, Vujić, Tatjana, Schvartz, Domitille, Sanchez, Jean-Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931063/
https://www.ncbi.nlm.nih.gov/pubmed/35301408
http://dx.doi.org/10.1038/s41598-022-08712-0