Clathrin-nanoparticles deliver BDNF to hippocampus and enhance neurogenesis, synaptogenesis and cognition in HIV/neuroAIDS mouse model

Brain derived neurotrophic factor (BDNF) promotes the growth, differentiation, maintenance and survival of neurons. These attributes make BDNF a potentially powerful therapeutic agent. However, its charge, instability in blood, and poor blood brain barrier (BBB) penetrability have impeded its develo...

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Detalles Bibliográficos
Autores principales: Vitaliano, Gordana D., Kim, Jae K., Kaufman, Marc J., Adam, Christopher W., Zeballos, Gonzalo, Shanmugavadivu, Abinaya, Subburaju, Sivan, McLaughlin, Jay P., Lukas, Scott E., Vitaliano, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931075/
https://www.ncbi.nlm.nih.gov/pubmed/35301411
http://dx.doi.org/10.1038/s42003-022-03177-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931075/
https://www.ncbi.nlm.nih.gov/pubmed/35301411
http://dx.doi.org/10.1038/s42003-022-03177-3

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