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Proteomic profiling based classification of CLL provides prognostication for modern therapy and identifies novel therapeutic targets

Protein expression for 384 total and post-translationally modified proteins was assessed in 871 CLL and MSBL patients and was integrated with clinical data to identify strategies for improving diagnostics and therapy, making this the largest CLL proteomics study to date. Proteomics identified six re...

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Detalles Bibliográficos
Autores principales: Griffen, Ti’ara L., Hoff, Fieke W., Qiu, Yihua, Lillard, James W., Ferrajoli, Alessandra, Thompson, Philip, Toro, Endurance, Ruiz, Kevin, Burger, Jan, Wierda, William, Kornblau, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931092/
https://www.ncbi.nlm.nih.gov/pubmed/35301276
http://dx.doi.org/10.1038/s41408-022-00623-7