Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging

During aging, the regenerative capacity of muscle stem cells (MuSCs) decreases, diminishing the ability of muscle to repair following injury. We found that the ability of MuSCs to regenerate is regulated by the primary cilium, a cellular protrusion that serves as a sensitive sensory organelle. Aboli...

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Detalles Bibliográficos
Autores principales: Palla, Adelaida R., Hilgendorf, Keren I., Yang, Ann V., Kerr, Jaclyn P., Hinken, Aaron C., Demeter, Janos, Kraft, Peggy, Mooney, Nancie A., Yucel, Nora, Burns, David M., Wang, Yu Xin, Jackson, Peter K., Blau, Helen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931095/
https://www.ncbi.nlm.nih.gov/pubmed/35301320
http://dx.doi.org/10.1038/s41467-022-29150-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931095/
https://www.ncbi.nlm.nih.gov/pubmed/35301320
http://dx.doi.org/10.1038/s41467-022-29150-6

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