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Antifungals influence the immune-related transcriptomic landscape of human monocytes after Aspergillus fumigatus infection

The heterogeneity of clinical responses to antifungals in aspergillosis is partially understood. We hypothesized that besides direct antifungal effects, these discrepancies may be related to different immunomodulatory profiles. Human THP-1 monocytes were coincubated in vitro with Aspergillus fumigat...

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Detalles Bibliográficos
Autores principales: Henry, Benoît, Klement, William, Gohir, Wajiha, Aguilar, Claire, Husain, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931103/
https://www.ncbi.nlm.nih.gov/pubmed/35301416
http://dx.doi.org/10.1038/s41598-022-08738-4