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Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1(G93A) mice

miRNAs are necessary for neuromuscular junction (NMJ) health; however, little is known about the proteins required for their activity in this regard. We examined expression of Argonaute 2 (Ago2) and miRNA biogenesis genes in skeletal muscles during development, following nerve injury and in the SOD1...

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Detalles Bibliográficos
Autores principales: Shapiro, Dillon, Massopust, Ryan, Taetzsch, Thomas, Valdez, Gregorio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931107/
https://www.ncbi.nlm.nih.gov/pubmed/35301367
http://dx.doi.org/10.1038/s41598-022-08455-y