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LC3B is an RNA-binding protein to trigger rapid mRNA degradation during autophagy

LC3/ATG8 has long been appreciated to play a central role in autophagy, by which a variety of cytoplasmic materials are delivered to lysosomes and eventually degraded. However, information on the molecular functions of LC3 in RNA biology is very limited. Here, we show that LC3B is an RNA-binding pro...

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Detalles Bibliográficos
Autores principales: Hwang, Hyun Jung, Ha, Hongseok, Lee, Ban Seok, Kim, Bong Heon, Song, Hyun Kyu, Kim, Yoon Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931120/
https://www.ncbi.nlm.nih.gov/pubmed/35302060
http://dx.doi.org/10.1038/s41467-022-29139-1