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Therapeutic targeting miR130b counteracts diffuse large B-cell lymphoma progression via OX40/OX40L-mediated interaction with Th17 cells

MicroRNAs (miRNAs) are involved in lymphoma progression by regulating the tumor microenvironment. Serum miR130b is overexpressed in diffuse large B-cell lymphoma (DLBCL), inducing Th17 cell alterations. To further illustrate its biological significance and therapeutic rationale, miR130b was detected...

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Detalles Bibliográficos
Autores principales: Sun, Rui, Zhang, Pei-Pei, Weng, Xiang-Qin, Gao, Xiao-Dong, Huang, Chuan-Xin, Wang, Li, Hu, Xiao-Xia, Xu, Peng-Peng, Cheng, Lin, Jiang, Lu, Fu, Di, Qu, Bin, Zhao, Yan, Feng, Yan, Dou, Hong-Jing, Zheng, Zhong, Zhao, Wei-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931122/
https://www.ncbi.nlm.nih.gov/pubmed/35301282
http://dx.doi.org/10.1038/s41392-022-00895-2