Force-enhanced biophysical connectivity of platelet β3 integrin signaling through Talin is predicted by steered molecular dynamics simulations

Platelet β3-integrin signaling through Talin is crucial in platelet transmembrane signaling, activation, adhesion, spreading and aggregation, and remains unclear in mechano-microenvironments. In order to examine Talin-β3 integrin biophysical connectivity, a series of “ramp-clamp” steered molecular d...

Descripción completa

Detalles Bibliográficos
Autores principales: Su, Shuixiu, Ling, Yingchen, Fang, Ying, Wu, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931153/
https://www.ncbi.nlm.nih.gov/pubmed/35301368
http://dx.doi.org/10.1038/s41598-022-08554-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931153/
https://www.ncbi.nlm.nih.gov/pubmed/35301368
http://dx.doi.org/10.1038/s41598-022-08554-w

Ejemplares similares