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Determination of the Interaction and Pharmacological Modulation of MCHR1 Signaling by the C-Terminus of MRAP2 Protein

Melanin concentrating hormone (MCH), an orexigenic neuropeptide, is primarily secreted by the hypothalamus and acts on its receptor, the melanin-concentrating hormone receptor 1 (MCHR1), to regulate appetite and energy homeostasis. The Melanocortin Receptor Accessory Protein 2 (MRAP2), a small singl...

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Detalles Bibliográficos
Autores principales: Wang, Meng, Zhai, Yue, Lei, Xiaowei, Xu, Jing, Jiang, Bopei, Kuang, Zhe, Zhang, Cong, Liu, Shangyun, Bian, Shan, Yang, Xiao-Mei, Zan, Tao, Jin, Li-Na, Li, Qingfeng, Zhang, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8931191/
https://www.ncbi.nlm.nih.gov/pubmed/35311242
http://dx.doi.org/10.3389/fendo.2022.848728